It was as early as July 1953, when the State of Andhra was settling down with its new identity in the brave young Republic of India that the Little Flower High School was established. With all their noble ideals and aspirations, the founding fathers perhaps never thought that the institution would grow to become a landmark in the modern city of Hyderabad. The Montfort Brothers of St. Gabriel under the able guidance of Rev. Bro. John of God set up the school with Rev. Bro. Britto as its first Principal. It was the need of the hour then, to provide sound education to a new generation of an independent nation. All Saints' High School at Gunfoundry with a history as old as 1855, was finding it difficult to cater to the perennial demand for admissions. Thus a new school was set up just across the main street, to mark the centenary celebrations of All Saints.

Diocese of Hyderabad first leased the land for 99 years. Later the ownership was transferred to the Society of the Montfort Brothers. Classes were started in temporary sheds from Kindergarten to Class VIII with two sections each. By 1957 there were classes till X with three sections each. It was recognised officially by the Government on the 16th of July 1960 under the Recognition No. 645/G1/60 as a minority institution. It received the ceiling grant up to September 1963. It however opted out of Grant- in-aid scheme from October 1963. The institution followed the HSLC course and later had the multi-purpose scheme from 1963 and came back to the SSC course according to the changing trends of the educational system.

Ever since those first few steps it has been a forward march led by noble and farsighted educationists. Each of the twelve Principals have contributed their valuable services not only in the infrastructure growth but also in planning and carrying out a comprehensive programme of child development. Humanistic values and academic excellence have always gone hand in hand.

Among the first buildings to be erected were the High School Block and the Main Building during the rectorate of Bro. Britto and Bro. Martialis from 1953 to 1964. Later during the rectorate of Bro. Dominic the Kindergarten Block was constructed. In 1972 when Bro. Vincent became the Rector, the New Building which comprises the students' dining hall, the indoor games hall and the Brothers' quarters was made. During the tenure of Bro. Claude, the Middle School Block with an in-built stage was built. Realising that students needed to be trained for entry into Professional Colleges, the Junior College was established in 1974 by Rev. Bro. Vincent. The students won top ranks in the state. Later, the campus had to be shifted to Uppal in 1982. With the passing of time, new developments and improvements were a matter of constant vigil and care. Bro. C. J. Thomas improved the audio - visual equipment, the science laboratory, and the acoustics in the auditorium and provided a library full of latest books on sciences and humanities. During the rectorate of Bro. C T. Paul, a complete computer centre with qualified staff was set up and computer classes were incorporated into the time - table.

When he was the Principal, Bro. John Kallarackal was the proud recipient of the 'Best Principal Award', the school was also adjudged as the 'Best School for the Academic Year 1996- 1997 '

During the tenure of Rev. Bro. Franky Noronha, the school witnessed a lot of infrastructure developments. LFHS was lauded as the best school in the twin cities and one of the ten best schools in India according to a survey conducted by " Outlook" magazine ( 2001 - 2002 & 2002 - 2003 ) consecutively. In August 2002 the school won the first prize at the state level the second prize at the National Level for Computer Literacy Excellence Awards. His Excellency A.P.J. Abdul Kalam the President of India gave away the award to Rev. Bro. Franky Norohna. On the same day our former student and national cricketer V.V.S. Laxman received the Arjuna Award from the President of India.

In 2006, Master Abhinav Ram and Master Rithvik Ramdass represented Asia in the Space Design Competition at the NASA Space Centre, Houston and were the runners up along with ten other students from AP.

This is but the framework, the edifice within which is enclosed the spirit of the school. The staff and students cannot go untouched by the holistic spirit, which creates an awareness of self and self in the society, the nation and the world. This awareness is conveyed through all the activities carefully programmed in the curriculum.

Catechism and moral instruction is given due importance. A leadership programme called the Montfortian Youth Leadership in Society (MYLS) was introduced which aims at orienting students for leadership in the society through peace and brotherhood. Guidance and counseling services is also a modern facility.

The institution celebrated its Silver Jubilee in 1978 and the Golden Jubilee in 2003.